Tulane University researchers will receive $3.35 million to continue their participation for the next five years in a major national study on kidney disease. Funded by the National Institute of Diabetes and Digestive and Kidney Diseases, one of the National Institutes of Health, the Chronic Renal Insufficiency Cohort Study has, since 2003, followed nearly 4,000 patients with chronic kidney disease through two phases of research at seven centers around the country including Tulane.
The third five-year long phase now kicking off is expanding the study’s scope to provide better understanding of how kidney disease progresses in members of an aging population. The researchers will focus on enrolling older participants, as it is mainly people in their early 60s who develop kidney failure requiring dialysis or a kidney transplant.
New recruits for the study’s third phase also will have milder forms of kidney disease than patients who participated in the earlier phases. Understanding the progression of kidney
Tulane scientists receive $3.35 million for kidney researchfunction decline and other clinical outcomes among patients with mild to moderate chronic kidney disease is a chief goal of the new phase of the study. The researchers want to understand the risk factors for the worsening of kidney functions in order to design new ways to prevent kidney disease from developing and worsening.
“This research has important public health and clinical implications,” says Jiang He, principal investigator at the Tulane study center and the Joseph S. Copes Chair and Professor in the Department in Epidemiology. “The study may reveal novel and reversible underlying factors for the progression of chronic kidney disease, cardiovascular disease, and other related outcomes.”
Co-investigators at Tulane for the Chronic Renal Insufficiency Cohort Study are Lee Hamm, executive vice dean of the Tulane School of Medicine, and Jing Chen, associate professor of medicine in the Tulane School of Medicine.
This article originally appeared in Tulane New Wave